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Pubmed 15159443 crewe hk, notley lm, wunsch rm, lennard ms, gillam em metabolism of tamoxifen by recombinant human cytochrome p450 enzymes formation of the 4-hydroxy, 4 -hydroxy and n-desmethyl metabolites and isomerization of trans-4-hydroxytamoxifen.

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Concomitant use of femara and tamoxifen by a daily dose of 20 mg leads to decrease of letrozole in blood concentrations.

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Do not take this medicine with any of the following medications -certain medicines for fungal infections like itraconazole this medicine may also interact with the following medications -alcohol -certain medicines for cholesterol like atorvastatin -certain medicines for coughs and colds -certain medicines to help you breathe better -cyclosporine -digoxin -epinephrine -grapefruit or grapefruit juice -methenamine -other medicines for fungal infection -sodium bicarbonate -some antibiotics like clarithromycin, erythromycin, and telithromycin -some medicines for an irregular heartbeat or other heart problems -some medicines for cancer, like lapatinib and tamoxifen -some medicines for hiv.

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